DNP = did not play in this round
| Region | Team 1 | Team 2 | ||
|---|---|---|---|---|
| Atlantic I | Bryn Mawr School (Baltimore, MD) | 62 | Gilman School Gold (Baltimore, MD) | 35 |
| Atlantic I | Gilman School Purple (Baltimore, MD) | 67 | The Boys' Latin School of Maryland (Baltimore, MD) | 56 |
| Atlantic I | Bye | 0 | Easton High School (Easton, MD) | 56 |
| Atlantic II | Gonzaga College High School Gold (Washington, DC) | 48 | Gonzaga College High School Purple (Washington, DC) | 39 |
| Atlantic II | Hayfield Secondary School (Alexandria, VA) | 65 | Thomas Jefferson HS for Science and Technology Gold (Alexandria, VA) | 94 |
| Atlantic II | Thomas Jefferson HS for Science and Technology Purple (Alexandria, VA) | 81 | Thomas A Edison High School (Alexandria, VA) | 39 |
| Atlantic III | Yorktown High School (Arlington, VA) | 68 | The Linsly School (Wheeling,, WV) | 52 |
| Atlantic III | Oakton High School Gold (Vienna, VA) | 38 | Flint Hill School (Oakton, VA) | 76 |
| Atlantic III | Fairfax High School (Fairfax, VA) | 35 | Oakton High School Purple (Vienna, VA) | 27 |
| Atlantic IV | Lake Braddock Secondary School Purple (Burke, VA) | 63 | Covenant Day School (Matthews, NC) | 41 |
| Atlantic IV | Trinity Upper School (Durham, NC) | 30 | Lake Braddock Secondary School Gold (Burke, VA) | 41 |
| Atlantic IV | Stuyvesant High School Purple (New York, NY) | 55 | Thomas Jefferson Classical Academy (Mooresboro, NC) | 39 |
| Central I | St. Mark's School of Texas Purple (Dallas, TX) | 70 | Trinity Valley School (Fort Worth, TX) | 61 |
| Central I | St. Mark's School of Texas Gold (Dallas, TX) | 65 | Greenhill Upper School (Addison, TX) | 72 |
| Central I | Fort Worth Country Day (Fort Worth, TX) | 57 | All Saints' Episcopal School (Fort Worth, TX) | 40 |
| Central II | Anderson HS (Austin, TX) | 34 | Aristoi Classical Academy (Katy, TX) | 40 |
| Central II | St. Thomas High School (Houston, TX) | DNP | Amarillo High School Gold (Amarillo, TX) | 40 |
| Central II | Amarillo High School Purple (Amarillo, TX) | 63 | St. John XXIII College Prep (Katy, TX) | 64 |
| Central III | St. Andrew's Episcopal School Purple (Austin, TX) | 36 | Austin High School Gold (Austin, TX) | DNP |
| Central III | Westlake High School Gold (Austin, TX) | 46 | Westlake High School Purple (Austin, TX) | 63 |
| Central III | Austin High School Purple (Austin, TX) | DNP | St. Andrew's Episcopal School Gold (Austin, TX) | 83 |
| Central IV | Klein Collins High School Purple (Klein, TX) | 57 | Saint Thomas' Episcopal Church & School (Houston, TX) | 68 |
| Central IV | Clements High School Gold (Sugar Land, TX) | 39 | St. John's School (Houston, TX) | 76 |
| Central IV | Clements High School Purple (Sugar Land, TX) | 56 | Klein Collins High School Gold (Klein, TX) | 56 |
| International/Nationwide | Emerson Latin (Online - South Korea) | 69 | App-Ark Institute Purple (Online - China) | DNP |
| International/Nationwide | App-Ark Institute Gold (Online - China) | 96 | IvyMind Academy Purple (Online - USA) | 98 |
| International/Nationwide | Bye | 0 | IvyMind Academy Gold (Online - USA) | 88 |
| Midwest I | Crown Point High School (Crown Point, IN) | 50 | Northwest Ohio Classical Academy (Toledo, OH) | 45 |
| Midwest I | Beaumont School (Cleveland Heights, OH) | 34 | Bexley Middle & High School (Columbus, OH) | 32 |
| Midwest I | Bye | 0 | Homestead High School (Fort Wayne, IN) | 50 |
| Midwest II | Covington Classical Academy (Covington, KY) | 56 | Saint Ursula Academy (Cincinnati, OH) | 44 |
| Midwest II | McNicholas HS Purple (Cincinnati, OH) | DNP | Covington Latin School (Covington, KY) | 34 |
| Midwest II | Sycamore Community Schools (Cincinnati, OH) | 36 | McNicholas HS Gold (Cincinnati, OH) | 34 |
| Midwest III | Parnassus Preparatory School (Maple Grove, MN) | 42 | Saint Louis Priory School (St. Louis, MO) | 48 |
| Midwest III | Homestead High School (Mequon, WI) | 53 | North Central High School (Indianapolis, IN) | 55 |
| Midwest III | Collinsville High School (Collinsville, IL) | 41 | Terre Haute South Vigo High School (Terre Haute, IN) | 56 |
| North | Brookfield Academy (Brookfield, WI) | 69 | Catholic Memorial High School Purple (Waukesha, WI) | 38 |
| North | Divine Savior Holy Angels HS (Milwaukee, WI) | 41 | University School of Milwaukee (River Hills, WI) | 37 |
| North | Brookfield East High School (Brookfield, WI) | 60 | Catholic Memorial High School Gold (Waukesha, WI) | 46 |
| Northeast I | Freeport High School (Freeport, ME) | 28 | Hampden Academy Purple (Hampden, ME) | 48 |
| Northeast I | John Bapst Memorial High School (Bangor, ME) | 37 | Goffstown High School (Goffstown, NH) | 31 |
| Northeast I | Hampden Academy Gold (Hampden, ME) | 35 | Fryeburg Academy (Fryeburg, ME) | 34 |
| Northeast II | Roxbury Latin (West Roxbury, MA) | 66 | Phillips Exeter Academy Purple (Exeter, NH) | 75 |
| Northeast II | Phillips Exeter Academy Gold (Exeter, NH) | 67 | Winchester High School (Winchester, MA) | 76 |
| Northeast II | St John's Preparatory School Purple (Danvers, MA) | 45 | Weston High School (Weston, MA) | 80 |
| Northeast III | Ridgewood High School Purple (Ridgewood, NJ) | 55 | Shrewsbury High School (Shrewsbury, MA) | 65 |
| Northeast III | Millburn High School Gold (Millburn, NJ) | 30 | Ridgewood High School Gold (Ridgewood, NJ) | DNP |
| Northeast III | Millburn High School Purple (Millburn, NJ) | 45 | Montclair Kimberley Academy—Upper School (Montclair, NJ) | 52 |
| Northeast IV | Harriton HS Gold (Bryn Mawr, PA) | 58 | Lower Merion High School Gold (Ardmore, PA) | 66 |
| Northeast IV | State College Area High SChool (State College, PA) | 32 | Harriton HS Purple (Bryn Mawr, PA) | 79 |
| Northeast IV | Lower Merion High School Purple (Ardmore, PA) | 31 | Boys' Latin of Philadelphia Charter High School (Philadelphia, PA) | 55 |
| Northeast V | Garden City High School Gold (Garden City, NY) | 47 | Fayetteville Manlius High School Gold (Manlius, NY) | 41 |
| Northeast V | Fayetteville Manlius High School Purple (Manlius, NY) | 46 | Garden City High School Purple (Garden City, NY) | 45 |
| Northeast V | St. Edward High School Gold (Lakewood, OH) | 52 | St. Edward High School Purple (Lakewood, OH) | 27 |
| Northeast VI | Owen J. Roberts High School Gold (Pottstown, PA) | 65 | Radnor High School Purple (Radnor, PA) | 47 |
| Northeast VI | Owen J. Roberts High School Purple (Pottstown, PA) | 37 | Radnor High School Gold (Radnor, PA) | 35 |
| Northeast VI | South Carroll High School (Sykesville, MD) | 18 | Mcdonogh School (Owings Mills, MD) | 43 |
| South | Houston High Purple (Germantown, TN) | DNP | Atchison Homeschool (Atchison, KS) | DNP |
| South | Houston High Gold (Germantown, TN) | 37 | Memphis University School Gold (Memphis, TN) | 63 |
| South | Clarksville High School (Clarksville, TN) | 53 | Memphis University School Purple (Memphis, TN) | 62 |
| Southeast I | Walton High School Gold (Marietta, GA) | 56 | Walton High School Purple (Marietta, GA) | 87 |
| Southeast I | Wheeler High School (Marietta, GA) | 51 | Northwest Classical Academy (Kennesaw, GA) | 54 |
| Southeast I | Milton High School (MIlton, GA) | 49 | The Walker School (Marietta, GA) | DNP |
| Southeast II | The King’s Academy (West Palm Bch, FL) | 27 | Berkeley Preparatory School (Tampa, FL) | 50 |
| Southeast II | The Classical Academy High School Gold (Colorado Springs, CO) | 34 | Plant High School (Tampa, FL) | 78 |
| Southeast II | Holy Trinity Episcopal Academy (Melbourne, FL) | 76 | Oak Hall School (Gainesville, FL) | 81 |
| Southeast III | BSHG JCL (Germantown, TN) | 72 | Midtown Classical (Tallahasee, FL) | 43 |
| Southeast III | Thomas County Schools (Thomasville, GA) | 29 | Altamont School (Birmingham, AL) | 43 |
| Southeast III | Maclay School Purple (Tallahassee, FL) | DNP | Maclay School Gold (Tallahassee, FL) | DNP |
| Southwest I | Phoenix Country Day School Purple (Paradise Vly, AZ) | 47 | Basis Ahwatukee (Phoenix, AZ) | 66 |
| Southwest I | Brophy College Preparatory Purple (Phoenix, AZ) | 57 | Brophy College Preparatory Gold (Phoenix, AZ) | 38 |
| Southwest I | Phoenix Country Day School Gold (Paradise Vly, AZ) | 57 | Trivium Prepatory Academy (Goodyear, AZ) | 54 |
| Southwest II | Thomas Jefferson High School Gold (Denver, CO) | 33 | Mullen High School (Denver, CO) | 38 |
| Southwest II | The Meadows School (Las Vegas, NV) | 41 | Thomas Jefferson High School Purple (Denver, CO) | 30 |
| Southwest II | Stuyvesant High School Gold (New York, NY) | 51 | The Classical Academy High School Purple (Colorado Springs, CO) | 41 |
| West I | Woodbridge High School (Irvine, CA) | 39 | University High School Gold (Irvine, CA) | 72 |
| West I | Sage Hill School Purple (Newport Coast, CA) | 67 | Pacifica Christian HS Santa Monica (Santa Monica, CA) | 37 |
| West I | University High School Purple (Irvine, CA) | 38 | Sage Hill School Gold (Newport Coast, CA) | 33 |
| West II | Clark High School (San Antonio, TX) | 57 | 'Iolani School (Honolulu, HI) | 53 |
| West II | St. Mary's Hall (San Antonio, TX) | 38 | The Harker School (San Jose, CA) | 71 |
| West II | Northside Health Careers HS Gold (San Antonio, TX) | 51 | Northside Health Careers HS Purple (San Antonio, TX) | 66 |