DNP = did not play in this round
| Region | Team 1 | Team 2 | ||
|---|---|---|---|---|
| Atlantic I | Dulaney High School Purple (Timonium, MD) | 43 | Bryn Mawr School (Baltimore, MD) | 57 |
| Atlantic I | The Boys' Latin School of Maryland (Baltimore, MD) | 44 | Gilman School Purple (Baltimore, MD) | 63 |
| Atlantic I | Gilman School Gold (Baltimore, MD) | 44 | Dulaney High School Gold (Timonium, MD) | 43 |
| Atlantic II | Gonzaga College High School Purple (Washington, DC) | 37 | Easton High School (Easton, MD) | 42 |
| Atlantic II | Gonzaga College High School Gold (Washington, DC) | 43 | Brophy College Preparatory (Phoenix, AZ) | 54 |
| Atlantic II | Yorktown High School (Arlington, VA) | 72 | South Carroll High School (Sykesville, MD) | 37 |
| Atlantic III | Thomas Jefferson HS for Science and Technology Purple (Alexandria, VA) | 84 | St. Stephen's and St. Agnes School Purple (Alexandria, VA) | 50 |
| Atlantic III | Thomas Jefferson HS for Science and Technology Gold (Alexandria, VA) | 89 | Thomas A Edison High School (Alexandria, VA) | 52 |
| Atlantic III | Hayfield Secondary School (Alexandria, VA) | 58 | St. Stephen's and St. Agnes School Gold (Alexandria, VA) | 57 |
| Atlantic IV | Oakton High School Purple (Vienna, VA) | 45 | Rock Ridge High School (Ashburn, VA) | 42 |
| Atlantic IV | Oakton High School Gold (Vienna, VA) | 51 | Lake Braddock Secondary School (Burke, VA) | 43 |
| Atlantic IV | Page High School (Greensboro, NC) | 75 | Flint Hill School (Oakton, VA) | 83 |
| Atlantic V | Dreher HS Gold (olumbia, SC) | 27 | Covenant Day School (Matthews, NC) | 65 |
| Atlantic V | Franklin Academy High School Gold (Wake Forest, NC) | 38 | Clarksville High School (Clarksville, TN) | 42 |
| Atlantic V | Franklin Academy High School Purple (Wake Forest, NC) | 36 | Dreher HS Purple (olumbia, SC) | 52 |
| Central I | Fort Worth Country Day (Fort Worth, TX) | 60 | Trinity Valley School (Fort Worth, TX) | 59 |
| Central I | Summit Country Day School (Cincinnati, OH) | 50 | Marcus HS Gold (Flower Mound, TX) | 44 |
| Central I | Marcus HS Purple (Flower Mound, TX) | 46 | All Saints' Episcopal School (Fort Worth, TX) | 46 |
| Central II | Northside Health Careers HS Gold (San Antonio, TX) | 78 | Northside Health Careers HS Purple (San Antonio, TX) | 71 |
| Central II | Clark High School (San Antonio, TX) | 65 | St. Mary's Hall Purple (San Antonio, TX) | DNP |
| Central II | Bye | 0 | St. Mary's Hall Gold (San Antonio, TX) | DNP |
| Central III | Anderson HS (Austin, TX) | 52 | S.F. Austin High School (Austin, TX) | 42 |
| Central III | St. Andrew's Episcopal School Purple (Austin, TX) | 47 | Providence Preparatory School Purple (Belton, TX) | 40 |
| Central III | Providence Preparatory School Gold (Belton, TX) | 47 | St. Andrew's Episcopal School Gold (Austin, TX) | 73 |
| Central IV | Saint Thomas' Episcopal Church & School Gold (Houston, TX) | 49 | Clements High School Purple (Sugar Land, TX) | 67 |
| Central IV | St. John's School Gold (Houston, TX) | 59 | Clements High School Gold (Sugar Land, TX) | 51 |
| Central IV | St. John's School Purple (Houston, TX) | 61 | Saint Thomas' Episcopal Church & School Purple (Houston, TX) | 67 |
| Central V | Klein Collins High School Purple (Klein, TX) | 71 | Klein Collins High School Gold (Klein, TX) | 57 |
| Central V | James E Taylor High School Purple (Katy, TX) | 37 | James E Taylor High School Gold (Katy, TX) | 41 |
| Central V | Aristoi Classical Academy (Katy, TX) | 53 | St. John XXIII College Preparatory (Katy, TX) | 54 |
| Midwest I | Columbus Academy (Gahanna, OH) | DNP | Northwest Ohio Classical Academy (Toledo, OH) | 42 |
| Midwest I | Bexley Middle & High School (Columbus, OH) | 44 | Beaumont School (Cleveland Heights, OH) | 33 |
| Midwest I | St. Edward High School (Lakewood, OH) | 26 | Homestead High School (Fort Wayne, IN) | 45 |
| Midwest II | Covington Classical Academy (Covington, KY) | 34 | Collinsville High School (Collinsville, IL) | 41 |
| Midwest II | St. Xavier High School (Cincinnati, OH) | 43 | Saint Louis Priory School (St. Louis, MO) | 38 |
| Midwest II | McNicholas High School (Cincinnati, OH) | 36 | North Central High School (Indianapolis, IN) | 44 |
| Midwest III | Lyons Township High School Purple (La Grange, IL) | 47 | University School of Milwaukee (River Hills, WI) | 56 |
| Midwest III | Loyola Academy (Wilmette, IL) | DNP | Parnassus Preparatory School (Maple Grove, MN) | 42 |
| Midwest III | Brookfield Academy (Brookfield, WI) | 67 | Brookfield East High School (Brookfield, WI) | 71 |
| Northeast I | Duxbury Middle/High School (Duxbury, MA) | 62 | St. John's Preparatory School Gold (Danvers, MA) | 40 |
| Northeast I | Hampden Academy Gold (Hampden, ME) | 61 | Wakefield Memorial High School (Wakefield, MA) | 43 |
| Northeast I | Hampden Academy Purple (Hampden, ME) | 45 | St. John's Preparatory School Purple (Danvers, MA) | 55 |
| Northeast II | Garden City High School Gold (Garden City, NY) | 55 | Stuyvesant High School Purple (New York, NY) | 59 |
| Northeast II | Garden City High School Purple (Garden City, NY) | 64 | Millburn High School Gold (Millburn, NJ) | 40 |
| Northeast II | Millburn High School Purple (Millburn, NJ) | 56 | Stuyvesant High School Gold (New York, NY) | 80 |
| Northeast III | Ridgewood High School Purple (Ridgewood, NJ) | 52 | Shrewsbury High School (Shrewsbury, MA) | 63 |
| Northeast III | Winchester High School (Winchester, MA) | 74 | Fayetteville-Manlius High School Gold (Manlius, NY) | 45 |
| Northeast III | Ridgewood High School Gold (Ridgewood, NJ) | 49 | Fayetteville-Manlius High School Purple (Manlius, NY) | 56 |
| Northeast IV | IvyMind Academy (Garnet Valley, PA) | 86 | Harriton HS Purple (Bryn Mawr, PA) | 87 |
| Northeast IV | Parkland JCL (Allentown, PA) | 47 | Lower Merion High School (Ardmore, PA) | 62 |
| Northeast IV | Harriton HS Gold (Bryn Mawr, PA) | 70 | Boys' Latin of Philadelphia Charter High School (Philadelphia, PA) | 35 |
| Northeast V | State College Area High School Gold (State College, PA) | 45 | Owen J. Roberts High School Purple (Pottstown, PA) | 34 |
| Northeast V | Shaler Area High School (Pittsburgh, PA) | 23 | The Linsly School (Wheeling,, WV) | 61 |
| Northeast V | Owen J. Roberts High School Gold (Pottstown, PA) | 48 | State College Area High School Purple (State College, PA) | 53 |
| Pacific I | Sage Hill School Purple (Newport Coast, CA) | 66 | 'Iolani School (Honolulu, HI) | 46 |
| Pacific I | Pacifica Christian HS Santa Monica (Santa Monica, CA) | 46 | Sage Hill School Gold (Newport Coast, CA) | 50 |
| Pacific I | The Harker School (San Jose, CA) | 71 | Bellarmine College Prep (San Jose, CA) | 30 |
| Pacific II | University High School Purple (Irvine, CA) | 74 | Stanford Online High School Gold (Berkeley, CA) | 52 |
| Pacific II | CHD Academy (Concord, CA) | 84 | University High School Gold (Irvine, CA) | 70 |
| Pacific II | Stanford Online High School Purple (Berkeley, CA) | 38 | St. Ignatius College Preparatory (San Francisco, CA) | 58 |
| Pacific III | Southern Nevada JCL (Meadows/Liberty) (Las Vegas, NV) | 46 | Basis Ahwatukee Purple (Phoenix, AZ) | 69 |
| Pacific III | Basis Ahwatukee Gold (Phoenix, AZ) | 67 | Phoenix Country Day School Purple (Paradise Vly, AZ) | 35 |
| Pacific III | Sage Ridge School (Reno, NV) | 40 | Phoenix Country Day School Gold (Paradise Vly, AZ) | 43 |
| Pacific IV | Amarillo High School Purple (Amarillo, TX) | 53 | Amarillo High School Gold (Amarillo, TX) | 38 |
| Pacific IV | The Classical Academy High School Gold (Colorado Springs, CO) | 46 | Thomas Jefferson High School Purple (Denver, CO) | 42 |
| Pacific IV | Thomas Jefferson High School Gold (Denver, CO) | 32 | The Classical Academy High School Purple (Colorado Springs, CO) | 52 |
| South I | BSHG JCL (Germantown, TN) | DNP | Bye | 0 |
| South I | Memphis University School Gold (Memphis, TN) | 39 | Blessed Sacrament Homeschool Group (Memphis, TN) | 73 |
| South I | Central Magnet School (Murfreesboro, TN) | DNP | Memphis University School Purple (Memphis, TN) | 65 |
| South II | Thomas County Schools (Thomasville, GA) | 59 | DeKalb School of the Arts (Avondale Estates, GA) | 39 |
| South II | George Walton Academy (Monroe, GA) | DNP | Milton High School (MIlton, GA) | 69 |
| South II | Walton High School Purple (Marietta, GA) | 90 | Walton High School Gold (Marietta, GA) | 75 |
| South III | Edgewood Jr. Sr. High School (Merritt Island, FL) | 53 | Society of Themistocles (Oviedo, FL) | 77 |
| South III | Oak Hall School (Gainesville, FL) | 78 | Midtown Classical (Tallahasee, FL) | 76 |
| South III | The Academy for Classical Education (Macon, GA) | 51 | Maclay School (Tallahassee, FL) | DNP |
| South IV | Alabama School of Fine Arts Gold (Birmingham, AL) | 45 | St. Mark's School of Texas (Dallas, TX) | 82 |
| South IV | Alabama School of Fine Arts Purple (Birmingham, AL) | 51 | Plant High School (Tampa, FL) | 72 |
| South IV | Episcopal School of Dallas (Dallas, TX) | 51 | Liberty Common High School (Fort Collins, CO) | 54 |
| South V | Greenhill Upper School (Addison, TX) | 50 | Dominion Academy (Dayton, OH) | 49 |
| South V | Wheeler High School Purple (Marietta, GA) | 70 | Houston High School (Germantown, TN) | DNP |
| South V | Wheeler High School Gold (Marietta, GA) | 37 | Bye | 0 |