DNP = did not play in this round
| Region | Team 1 | Team 2 | ||
|---|---|---|---|---|
| Atlantic | Welsh Valley Middle School Purple (Narberth, PA) | 82 | Boys' Latin of Philadelphia Middle School Gold (Philadelphia, PA) | 58 |
| Atlantic | Black Rock Middle School (Villanova, PA) | 73 | Welsh Valley Middle School Gold (Narberth, PA) | 79 |
| Atlantic | Bala Cynwyd Middle School (Bala Cynwyd, PA) | 79 | Bye | 0 |
| Central I | Greenhill Middle School Purple (Addison, TX) | 73 | St Mark's School of Texas Gold (DALLAS, TX) | 78 |
| Central I | Aristoi Classical Academy (Katy, TX) | 62 | St Mark's School of Texas Purple (DALLAS, TX) | 83 |
| Central I | Fort Worth Country Day (Fort Worth, TX) | 78 | Greenhill Middle School Gold (Addison, TX) | 67 |
| Central II | Brookfield Academy Gold (Brookfield, WI) | 80 | Saint Thomas' Episcopal Church & School (Houston, TX) | DNP |
| Central II | St. John's School (Middle) (Houston, TX) | DNP | Brookfield Academy Purple (Brookfield, WI) | 88 |
| Central II | BSHG JCL (Germantown, TN) | 86 | Bye | 0 |
| Midwest I | Northwest Ohio Classical Academy Gold (Toledo, OH) | 58 | Northwest Ohio Classical Academy Purple (Toledo, OH) | 58 |
| Midwest I | Canterbury School (Fort Wayne, IN) | 92 | Midwest Academy for Gifted Education (Chicago, IL) | 89 |
| Midwest I | Woodside Middle School (Fort Wayne, IN) | 65 | Liberty Common Junior High School (Fort Collins, CO) | 83 |
| Midwest II | Dickerson Middle School (Marietta, GA) | 80 | Lake Braddock Secondary School (Burke, VA) | 63 |
| Midwest II | Dominion Academy (Dayton, OH) | DNP | Bexley Middle & High School (Columbus, OH) | 81 |
| Midwest II | Robious Middle School Purple (Midlothian, VA) | 71 | Robious Middle School Gold (Midlothian, VA) | 82 |
| Northeast | The Linsly School (Wheeling,, WV) | 69 | Benjamin Franklin MIddle School Gold (Ridgewod, NJ) | 82 |
| Northeast | Benjamin Franklin MIddle School Purple (Ridgewod, NJ) | 74 | Waynflete School (Portland, ME) | 73 |
| Northeast | Dutchess Day School (Millbrook, NY) | 72 | Bye | 0 |
| Pacific | App-Ark Institute Gold (Online - China) | DNP | 'Iolani School Purple (Honolulu, HI) | 63 |
| Pacific | Mirman School Gold (Los Angeles, CA) | 78 | 'Iolani School Gold (Honolulu, HI) | 54 |
| Pacific | App-Ark Institute Purple (Online - China) | DNP | Mirman School Purple (Los Angeles, CA) | 82 |
| Southeast I | The King’s Academy Gold (West Palm Bch, FL) | 60 | Saint Stephen's Episcopal School Gold (SARASOTA, FL) | 51 |
| Southeast I | Oak Hall School (Gainesville, FL) | 82 | St John's Episcopal Parish Day School (Tampa, FL) | 71 |
| Southeast I | Saint Stephen's Episcopal School Purple (SARASOTA, FL) | 70 | The King’s Academy Purple (West Palm Bch, FL) | 67 |
| Southeast II | Midtown Classical (Tallahasee, FL) | 96 | Thomas Jefferson Classical Academy (Mooresboro, NC) | 77 |
| Southeast II | Dodgen Middle School Gold (Marietta, GA) | 81 | Thomas County Schools (Thomasville, GA) | 55 |
| Southeast II | Northwest Classical Academy (Kennesaw, GA) | 83 | Dodgen Middle School Purple (Marietta, GA) | 78 |
| Southeast III | Lakewood Montessori Middle School Purple (Durham, NC) | 67 | St. David's School Gold (Raleigh, NC) | 64 |
| Southeast III | Altamont School (Birmingham, AL) | 47 | Lakewood Montessori Middle School Gold (Durham, NC) | 66 |
| Southeast III | Trinity School of Durham and Chapel Hill (Middle School) (Durham, NC) | 78 | St. David's School Purple (Raleigh, NC) | 67 |
| West I | Harker Middle School Gold (San Jose, CA) | 90 | The Meadows School Gold (Las Vegas, NV) | 64 |
| West I | The Meadows School Purple (Las Vegas, NV) | 66 | St. Andrew's Episcopal Middle School Purple (Austin, TX) | 76 |
| West I | Harker Middle School Purple (San Jose, CA) | 88 | St. Andrew's Episcopal Middle School Gold (Austin, TX) | 66 |
| West II | Phoenix Country Day School (Paradise Valley, AZ) | 75 | BASIS Ahwatukee/Phoenix Purple (Phoenix, AZ) | 63 |
| West II | Brophy College Preparatory (Phoenix, AZ) | 65 | BASIS Ahwatukee Gold (Phoenix, AZ) | 94 |
| West II | Trivium Prepatory Academy (Goodyear, AZ) | 84 | Bye | 0 |