DNP = did not play in this round
| Region | Team 1 | Team 2 | ||
|---|---|---|---|---|
| Central I | St. Mark's School of Texas Purple (Dallas, TX) | 76 | Murchison MS (Austin, TX) | 52 |
| Central I | Greenhill Middle School Gold (Addison, TX) | 58 | St. Mark's School of Texas Gold (Dallas, TX) | 75 |
| Central I | Greenhill Middle School Purple (Addison, TX) | 72 | Fort Worth Country Day Middle (Fort Worth, TX) | 52 |
| Central II | Memphis University School Gold (Memphis, TN) | 64 | Saint Thomas' Episcopal Church & School Purple (Houston, TX) | 77 |
| Central II | Memphis University School Purple (Memphis, TN) | 56 | Saint Thomas' Episcopal Church & School Gold (Houston, TX) | 61 |
| Central II | Aristoi Classical Academy (Katy, TX) | 51 | Blessed Sacrament Homeschool Group (Memphis, TN) | 75 |
| Midwest I | The Stanley Clark School Purple (South Bend, IN) | 53 | Brookfield Academy Purple (Brookfield, WI) | 70 |
| Midwest I | Canterbury School (Fort Wayne, IN) | 80 | The Stanley Clark School Gold (South Bend, IN) | DNP |
| Midwest I | Northwest Ohio Classical Academy (Toledo, OH) | 53 | Brookfield Academy Gold (Brookfield, WI) | 60 |
| Midwest II | Lake Braddock Secondary School Purple (Burke, VA) | 46 | Lake Braddock Secondary School Gold (Burke, VA) | 52 |
| Midwest II | Summit Country Day School (Cincinnati, OH) | DNP | Robious Middle School Purple (Midlothian, VA) | 63 |
| Midwest II | Robious Middle School Gold (Midlothian, VA) | 64 | Columbus Academy (Gahanna, OH) | 56 |
| Northeast I | Black Rock Middle School Purple (Villanova, PA) | 47 | Bye | 0 |
| Northeast I | Bala Cynwyd Middle School Purple (Bala Cynwyd, PA) | 59 | Black Rock Middle School Gold (Villanova, PA) | 52 |
| Northeast I | Bala Cynwyd Middle School Gold (Bala Cynwyd, PA) | 57 | Welsh Valley Middle School Purple (Narberth, PA) | 56 |
| Northeast II | Oak Middle School (Shrewsbury, MA) | 56 | Ridgewood High School Gold (Ridgewod, NJ) | 47 |
| Northeast II | Ridgewood High School Purple (Ridgewod, NJ) | 66 | Welsh Valley Middle School Gold (Narberth, PA) | 61 |
| Northeast II | Shaler Area High School (Glenshaw, PA) | 38 | Central Magnet School (Murfreesboro, TN) | DNP |
| Pacific I | Sage Ridge School (Reno, NV) | DNP | Mirman School Purple (Los Angeles, CA) | 66 |
| Pacific I | CHD Academy (Concord, CA) | 71 | Harker Middle School Purple (San Jose, CA) | 72 |
| Pacific I | Mirman School Gold (Los Angeles, CA) | 69 | Harker Middle School Gold (San Jose, CA) | 72 |
| Pacific II | Trivium Preparatory Academy (Goodyear, AZ) | 57 | BASIS Ahwatukee Gold (Phoenix, AZ) | 76 |
| Pacific II | Phoenix Country Day School Purple (Paradise Vly, AZ) | 70 | The Meadows School (Las Vegas, NV) | 67 |
| Pacific II | Phoenix Country Day School Gold (Paradise Vly, AZ) | 44 | BASIS Ahwatukee Purple (Phoenix, AZ) | 57 |
| South I | Dodgen Middle School PUrple (Marietta, GA) | 74 | North Gwinnett Middle School (Sugar Hill, GA) | 41 |
| South I | Dodgen Middle School Gold (Marietta, GA) | 58 | Dickerson Middle School Gold (Marietta, GA) | 66 |
| South I | Dickerson Middle School Purple (Marietta, GA) | 67 | The Walker School (Marietta, GA) | 78 |
| South II | Thomas Hart Academy (Hartsville, SC) | DNP | Midtown Classical (Tallahasee, FL) | 79 |
| South II | Oak Hall School (Gainesville, FL) | 71 | Society of Themistocles (Oviedo, FL) | 58 |
| South II | Holy Trinity Classical Christian School (Beaufort, SC) | DNP | St John's Episcopal Parish Day School (Tampa, FL) | 49 |
| South III | Lakewood Montessori Middle School Gold (Durham, NC) | 47 | BSHG JCL (Germantown, TN) | DNP |
| South III | Louisville Classical Academy (Louisville, KY) | 59 | St Timothy's Episcopal School (Raleigh, NC) | 64 |
| South III | Thales Academy Rolesville (Rolesville, NC) | 55 | Lakewood Montessori Middle School Purple (Durham, NC) | 66 |